Absence of sperms in a man’s semen is referred as obstructive azoospermia, as a result of problems with sperm delivery. Obstructive azoospermia accounts for approximately 40 % of azoospermia cases. Most generally, obstructive azoospermia will results from the previous vasectomy. Obstructive azoospermia is a usual cause of male infertility and may results from the infection, iatrogenic injury or congenital anomalies Microsurgical vasal reconstruction is a most appropriate treatment for many cases of obstructive azoospermia.
Troubles with the ductal system or issues related with ejaculation may generally cause obstructive azoospermia. The ducts can be blocked or missing or the man could have an lack of the vas deferens, the tube that transports sperm for ejaculation.
Obstructive azoospermia may also be caused by trouble with ejaculation. There may be problems with discharge, the procedure by which the sperm is deposited into the urethra ahead of ejaculation. This can be caused by neurological injure from spinal cord injury, surgery or diabetes.
The diagnosis test may include a history, a physical examination and thorough evaluation of testes and the scrotum, laboratory tests and probably imaging tests. History may include the general health, libido sexual activity, sexual health and past fertility. Past exposure to many chemicals or drugs wants to be queried includes medical agents like antibiotics, hormone and steroid therapy, 5-ASA inhibitors), recreational drugs like excessive alocholic, alpha-blockers, pesticides, 5 alpha-reductase inhibitors, chemotherapeutic agents and heat exposure of the testes.
Congenital absence of the vas deferens can be detected by physical examination and can be concluded by a transrectal ultrasound (TRUS).
Men who are suffering with obstructive azoospermia needs surgery to rectify the obstruction. This surgery can make natural pregnancy achievable without any assisted reproductive technology like IUI, IVF and ICSI. A treatment known as vasoepididymostomy needs to be done in men with an epididymal obstruction, for men who are affected with ejaculatory duct obstruction, a procedure called the transurethral resection of the ejaculatory duct (TURED) may be highly suggested.