Intracavernosal injection therapy is an efficient therapy for men who are suffering with erectile dysfunction (ED) and who cannot take oral medications or for whom oral medications are not effective. Initial dosing and dosage concentration will differ for each and every man.
Injections are injected by a 1 ml syringe along with 27 to 30-gauge needle and 1/2 or 5/8-inch length, The injection can be given any place from the base of the penis to 2/3rd of the way down the penile shaft at the 10 o’clock & 2 o’clock positions on upper side of penis which is away from the urethra and the head of penis. Injections were rotated in that region and the side of the injection is interchange with each injection. So many factors are considered when determining a initial dose and titrating medication for the patients. The aim of this procedure is to create sufficient erection for sexual relations, while reducing side effects like pain or priapism.
The major common side effects are a mild to temperate dull ache, which starts 5 to 20 minutes after the injection. This ache will be more by standing, and subsides when the erection is disappeared. It is supposed that the ache is because of the potassium included in the medication.
This is substitute for the men who won’t tolerate this ache is by using off label a mixture of Alprostadil, Papaverine and Phentolamine. Which is very painless and effective. When needle was stuck into patient’s body, a small bump may develop at the place of the injection. Occasionally, a small nodule or lump can build up if the same site is injected repeatedly. Sometimes, plaque or scarring of the penis can occur. Rarely, the medication may cause a painful, sustained, prolonged erection, known as priapism. Priapism (a rigid erection for more than 4 to 8 hours) it requires instant medical attention, but is easily reversed when treated early.